New ICD-10-PCS Code Streamlines Documentation for AI Sepsis Diagnostics

A New Era in Sepsis Diagnosis with ICD-10-PCS Code

In a ground-breaking development for healthcare documentation, the Centers for Medicare & Medicaid Services (CMS) has released its FY 2026 ICD-10-CM Diagnosis Code Files and ICD-10-PCS Procedure Code Files. This release marks a significant milestone in how sepsis care will be documented moving forward, blending technology with clinical practices to improve patient outcomes. The new coding structure is designed to facilitate the use of AI sepsis diagnostic technologies, specifically the Sepsis ImmunoScore by Prenosis.

A Game-Changer for Healthcare Facilities

Effective from October 1, 2025, hospitals across the United States will gain access to a newly approved code: XXEZXCB, which pertains to the measurement of infections, computer-aided triage, and notification. This addition not only enhances the documentation of the Sepsis ImmunoScore but also represents an essential step towards integrating advanced technology into the healthcare system’s coding practices.

Having a specific ICD-10-PCS code for the Sepsis ImmunoScore serves two main functions. Firstly, it ensures that healthcare facilities can accurately document their utilization of this innovative diagnostic tool, streamlining the tracking and reporting process. Secondly, it creates a necessary foundation for hospitals seeking involvement in the New Technology Add-on Payment (NTAP) submission processes, which are critical for financial reimbursement.

Importance of Accurate Documentation in Healthcare

Robin Carver, Senior Vice President of Commercialization for Prenosis, commented on the significance of this development: "This official code recognition validates the clinical significance of advanced sepsis diagnostics and provides hospitals with the documentation framework needed to support improved patient outcomes." The implications of accurately coding and tracking these technologies are profound, offering a clear pathway for clinical quality measurement and optimizing reimbursement opportunities.

With the implementation of the Sepsis ImmunoScore, healthcare organizations can seamlessly incorporate this diagnostic tool into their existing systems. This integration not only aids in the detection and management of sepsis but fosters an environment where evidence-based innovations are prioritized, ultimately elevating patient care standards.

About Prenosis and the Sepsis ImmunoScore

Prenosis, Inc. is at the forefront of revolutionizing healthcare standards for critical conditions through the use of biological-based technologies. Their mission is straightforward; to move away from a generic healthcare model and tailor treatments to the unique biological characteristics of each patient.

By leveraging deep data and artificial intelligence, Prenosis develops tools designed to enhance clinical diagnostics for serious health issues, with a leading example being the Sepsis ImmunoScore™, recognized as the first FDA-authorized AI diagnostic tool for sepsis. This innovative approach sets Prenosis apart in a world where personalized healthcare solutions are increasingly vital.

As hospitals prepare to implement the new ICD-10-PCS code and its associated processes, the healthcare industry's commitment to adopting advanced diagnostic techniques is more critical than ever. The combination of technology and innovative coding promises to enhance not just awareness but also the effectiveness of sepsis detection and management across the healthcare spectrum.

For more comprehensive information about Prenosis and their innovative diagnostics, visit prenosis.com or connect with them on LinkedIn.