#Japan #Tokyo #genome editing #MycoGenome #Campus Create

MycoGenome and Campus Create Union

In an exciting move for the biotechnology sector, MycoGenome Corporation, headquartered in Chiyoda, Tokyo, has entered into a business partnership with Campus Create Corporation, located in Chofu, Tokyo. This collaboration aims to leverage MycoGenome’s groundbreaking genome editing technologies, developed from the latest research at the Tokyo University of Science, to facilitate the social implementation of new products and services.

Background of Genome Editing Technology

In recent years, genome editing has gained significant attention due to its potential to revolutionize various fields, including medical treatments, drug development, regenerative medicine, and solutions to agricultural challenges. Technologies like CRISPR/Cas9 have enabled researchers to manipulate genetic information with unprecedented precision. However, the application of genome editing to fungi (including mushrooms, molds, and yeasts) has faced industry challenges due to several technical barriers.

MycoGenome has cracked this code by utilizing research led by Professors Takashi Kamakura and Takayuki Arazoe from the Department of Life Sciences at Tokyo University of Science, creating a fully domestic genome editing technology. This innovation allows for genome editing approaches that previously seemed impossible with fungi. As a result, it offers the capability to enhance the production efficiency of microorganisms that yield pharmaceuticals and valuable substances. The applications extend to improving fermentation processes for yeast and developing strains that enhance flavors. Moreover, it supports initiatives within the increasing bioenergy sector, promising a wide array of technical advancements and solutions to industry challenges.

Expanding Horizons with Campus Create

Campus Create has been an instrumental player in the promotion of research results into society for over 25 years, specializing in matching university innovations with corporate needs, providing commercialization support, and facilitating collaborative research. Recognizing the potential impact of MycoGenome's advanced genome editing technology, Campus Create is committed to accelerating the implementation of this technology within various industries. Through their combined efforts, both companies aim to address pressing societal issues and enhance industrial innovation.

Key Features of MycoGenome’s Advanced Genome Editing Technology

MycoGenome has developed a novel, industry-appropriate, non-recombinant genome editing technique for fungi, building on years of microbial research. Let's explore the key features that set this technology apart:

Feature 1: Non-Recombinant Editing Technology

Traditional fungal genome editing typically involves introducing foreign DNA into the genome, which poses challenges concerning societal acceptance and regulatory compliance. MycoGenome addresses this issue by utilizing self-replicating vectors, which facilitate a non-recombinant editing approach. This innovation allows for the social implementation of changes while effectively navigating the existing GMO regulations.

Feature 2: High Transformation Efficiency

The self-replicating vector developed by MycoGenome boasts significantly higher transformation efficiency compared to conventional fungal vectors. This advancement enables rapid and stable introduction of target genes into various fungi, establishing a robust technological foundation for developing high-yield, reproducibly effective strains required for industrial applications.

Feature 3: Limited Licensing Risks for Intellectual Property

Many conventional genome editing techniques, including CRISPR/Cas9, encounter difficulties in bypassing multiple costly patent licenses. However, MycoGenome's proprietary technology, based on its extensive patent portfolio, offers a design that significantly reduces licensing risks for implementing companies.

Vision of MycoGenome

MycoGenome’s mission is to unlock the full potential of fungi and drive innovation across diverse sectors, including food, agriculture, medicine, environment, and energy. By harnessing the unique MycoEdita technology, they are establishing unprecedented genome editing methodologies, free from reliance on traditional CRISPR/Cas9 techniques, which paves the way for creating new markets in microbial biotechnology.

About MycoGenome Corporation

• - Company Name: MycoGenome Corporation
• - Address: 1-13-11 Fujimi, Chiyoda, Tokyo
• - CEO: Hayashi Osamu
• - Founded: December 2024
• - Website: MycoGenome

About Campus Create Corporation

• - Company Name: Campus Create Corporation
• - Address: 1-5-1 Chofugaoka, Chofu, Tokyo, Inside the National Institute of Telecommunications
• - CEO: Takahashi Megumi
• - Founded: September 1999
• - Website: Campus Create