#Longevity #Exosomes #Regenesome

Celebrating One Year of Regenesome: Achievements and Future Directions

On July 31, 2025, Regenesome Inc., a subsidiary of Space Seed Holdings Co., Ltd., hosted its first anniversary event titled "Regenesome 1st Anniversary – Achievement Report and Commemorative Party" at the Takanawa Gateway Link Scholars' Hub (LiSH) Studio 1 in Tokyo. Established in July 2024, Regenesome focuses on creating practical solutions to address issues related to aging through regenerative medicine and healthcare technologies.

Throughout the event, the company shared insights into its research and development achievements over the past year and outlined its future challenges in the field of longevity research.

Highlights from the Achievement Report

Introduction by CEO Gentaro Sakuma

CEO Gentaro Sakuma opened the event with an overview of Regenesome's founding history and its strategic direction. He shared the company's mission, vision, and values, emphasizing its focus on tackling age-related health challenges that span both Earth and space.

• - Mission: To provide anti-aging technologies applicable for terrestrial use in anticipation of expanding living environments on the Moon by 2040.
• - Vision: To demonstrate these anti-aging technologies by 2030.
• - Values: Fostering knowledge on exosomes, establishing a network in space science, and implementing aging research in society.

The CEO also detailed Regenesome's diverse business portfolio, which ranges from contract research based on exosome studies to the development of healthcare products and medical devices, including advancements in cancer treatment through collaborations with institutions like Tohoku University and Tokyo Science University.

Research Presentation Highlights

Several significant research findings were presented during the event:

• - Age Prediction Using DNA Methylation Markers: Daiko Okada, a specially appointed assistant professor from Gifu University, showcased a novel approach utilizing comprehensive DNA methylation data to develop an "epigenetic clock." This technique, leveraging saliva for predictions, demonstrated high accuracy with a Pearson correlation of 0.90, overcoming previous interpretability challenges.
• - Improving Aging through Hypoxic Environments: Taku Nakai from Tohoku University reported on research within the "Aging Care Space" project, discussing the implications of low-oxygen environments on cellular function and aging, and its potential applications.
• - Analysis of Real-World Data in Cognitive Disorders: Chaewoo Choi from Nippon System Technology Co., Ltd. unveiled results from large-scale data analysis in dementia research, indicating new potential metrics for application in real clinical settings.
• - Introducing the SAISEI Regenosome Supplement: Marketing Manager Mio Soma introduced the newly launched SAISEI supplement, which combines various components like Euglena gracilis, sake lees powder, Kalahari watermelon powder, and purified ergothioneine, designed for scientifically backed aging care.
• - Updates on Research and Development: CEO Kengo Suzuki discussed innovative research utilizing nanoparticles to control aging, particularly focusing on the application of sake-derived nanoparticles, known as "SAKESOME," and the development of products harnessing anti-aging compounds found in sake.

Networking and Commemorative Celebrations

Following the achievement reports, the anniversary party fostered networking among researchers, corporate representatives, and government officials, enhancing the collaboration between academia, industry, and government. Lightning talks introduced initiatives like the Citizen Science platform