#None #Quotient Sciences #NGT Biopharma #drug solubility

Upcoming Webinar: Enhancing Drug Solubility

Overview

In the fast-evolving pharmaceutical landscape, drug solubility remains a critical hurdle that challenges the development of small molecule drugs. A significant proportion—estimated at 80-90%—of molecules in development grapple with poor solubility, which ultimately affects bioavailability and clinical performance. To address this pressing issue, an upcoming free webinar, hosted by Xtalks, will delve into integrated formulation strategies that can effectively alleviate drug solubility concerns throughout the stages of development and clinical supply.

What to Expect

This insightful session will feature prominent speakers including Robert Cornog, Senior Director of Product Development at Quotient Sciences; Mark A. Krook, PhD, from NGT Biopharma Consultants; and Andrew Parker, PhD, an Executive Drug Development Consultant at Quotient Sciences. They will provide a comprehensive analysis of how understanding a molecule's physicochemical properties, coupled with flexible clinical development plans, can influence the choice of formulation techniques such as hot melt extrusion (HME), spray drying, lipid-based formulations, or particle size reduction.

Key Highlights of the Webinar

1. Understanding Formulation Techniques: Learn about various methods such as HME and spray dried dispersions (SDD), which are essential in enhancing the solubility of drug compounds.
2. Importance of Early Planning: Discover how proactive formulation and manufacturing planning mitigate risks in scale-up processes and streamline technology transfer.
3. Regulatory and Commercial Considerations: The session will emphasize the regulatory environment and how formulation decisions can affect commercial readiness for drug products.
4. Real-World Case Studies: Participants will gain insights through real-world examples demonstrating successful navigation of solubility challenges that can accelerate drug development processes.

The Need for Effective Strategies

The challenges presented by poor drug solubility are not trivial. As sponsors increasingly seek integrated strategies, the emphasis on informed decision-making becomes paramount. The upcoming session aims to demystify common formulation approaches and offer attendees actionable insights on selecting the best strategies for optimizing drug solubility.

Registration Details

This live webinar is set to take place on Tuesday, September 8, 2026, at 10am EDT (4pm CEST). Participants will have a unique opportunity to learn from industry leaders and engage in discussions surrounding formulation and scale-up strategies. Interested individuals can register for the event here.

About Xtalks

Xtalks is renowned within the life sciences community for empowering professionals across various sectors—pharma, biotech, medtech, and healthcare—by providing them with vital industry knowledge and insights that foster informed decision-making. Participants can expect high-quality content, including news updates, webinars, podcasts, and more, tailored to maintain relevance in a rapidly changing landscape.

Conclusion

By joining this webinar, participants will equip themselves with insights that can significantly impact their approaches to drug solubility during development phases. Navigating the complexities of formulation choices with the guidance of industry experts will undoubtedly pave the way for more efficient and effective drug development strategies.