NERON and RIKEN Collaboration
2025-08-08 11:32:52

NERON Collaborates with RIKEN to Enhance Mental Health Through Gut Microbiome Research

NERON and RIKEN: Pioneering Mental Health Research



In an exciting development, NERON Co., Ltd., based in Shibuya, Tokyo, has forged a partnership with the RIKEN Center for Integrative Medical Sciences (RIKEN IMS) to delve into the intricate relationship between gut microbiota, the intestine, and brain function. Spearheaded by Dr. Hiroshi Ohno, the Mucosal System Research Team leader at RIKEN, this collaboration aims to explore mechanisms that could lead to significant improvements in mental health.

The Rationale Behind the Research


As global mental health concerns continue to rise, the importance of understanding the gut-brain axis has become more evident. Recent studies have illuminated how the gut microbiome influences brain function and emotional wellbeing. This research is crucial as it opens new potential avenues for mental health treatment that do not rely solely on pharmaceuticals.

NERON has been developing its proprietary gut microbiome cocktail, known as ECB (Enhancing Cognitive Benefits), aimed at fostering mental wellbeing. By integrating NERON’s innovative products with RIKEN IMS’s cutting-edge gut immunology research, the goal is to create scientifically-backed solutions for addressing mental health issues such as depression and stress-related disorders.

Meet the Expert Behind the Research


Dr. Hiroshi Ohno, a prominent figure in the field of gut microbiome research, is leading this ambitious project. A graduate of Chiba University School of Medicine in 1983, he has a wealth of experience, including a fellowship at the National Institutes of Health (NIH) from 1994 to 1997. Dr. Ohno has previously served as an associate professor at Chiba University and a professor at the Kanazawa University Cancer Research Institute. Since 2018, he has been at the helm of the Mucosal System Research Team at RIKEN IMS, contributing invaluable insights into the interactions between gut immunity and microbiota.

His accolades include the Purple Ribbon Medal (2023), the Ando Momofuku Prize, the Berzelius Prize, and the Noguchi Hideyo Memorial Prize, further establishing him as a trailblazer in connecting basic and clinical research.

Future Prospects of the Research


Through this joint research initiative, both teams will focus on deciphering the mechanisms underlying the gut-brain relationship and conducting integrated analyses across immune, metabolic, and neural networks. With an eye towards clinical applications in Japan and abroad, the research aims to create a robust evidence base that supports the use of gut microbiota in mental health improvement strategies. The ultimate goal is to develop effective mental health solutions that could be introduced to the global market, offering significant benefits to individuals seeking alternative treatments.

About NERON Co., Ltd.


NERON Co., Ltd. was founded with the vision of enabling everyone worldwide to live a secure, healthy, and fulfilling life. The company is committed to developing innovative products that leverage the gut microbiome to enhance mental well-being. Through its unique gut microbiome cocktail technology, NERON aims to contribute to the health of both mind and body, addressing the needs of an aging society more effectively.

Company Overview


  • - Name: NERON Co., Ltd.
  • - Location: Shibuya, Tokyo
  • - CEO: Kyosuke Nagasaki
  • - Established: October 2022
  • - Business Focus: Research, development, and sales of products utilizing gut microbiota
  • - Official Website: NERON

In conclusion, the collaboration between NERON and RIKEN marks a significant step towards understanding one of the most complex and crucial relationships in human health. By blending innovative product development with rigorous scientific inquiry, they are poised to make a lasting impact on the field of mental health and wellbeing.


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Topics Health)

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