Lexogen Unveils Advanced miRVEL Discovery RNA-Seq Kit for Biomarker Research
Lexogen Launches Groundbreaking miRVEL Discovery Kit
Lexogen, a trailblazer in RNA sequencing technology, proudly announces the launch of its innovative miRVEL Discovery Small RNA-Seq Library Prep Kit. This state-of-the-art kit is specifically tailored for the discovery of small RNAs (sRNAs) and the study of biomarkers, catering particularly to researchers dealing with low-input biofluid samples, such as blood and plasma.
Enhancing Discoveries in Biofluid Transcriptomics
The miRVEL Discovery kit is a breakthrough in the world of transcriptomics by maximizing the potential of circulating sRNAs found in biofluids. These small RNAs are critical for diagnostic and prognostic applications across a range of diseases, including various cancers and neurodegenerative disorders. Because biofluid samples often contain significant levels of abundant RNA species, they may obscure the small RNAs of interest during sequencing experiments. The miRVEL Discovery kit is designed to suppress the incorporation of hY4 Y RNA, which enhances the clarity of sequencing results and enables researchers to gain deeper insights into transcriptomic profiles.
High Precision Through UMI Integration
A standout feature of the miRVEL Discovery kit is its incorporation of Unique Molecular Identifiers (UMIs). This advanced technology effectively eradicates PCR duplicates, leading to more accurate and unbiased quantification of small RNAs. Furthermore, its use of 10 nt unique dual indices (UDIs) significantly minimizes issues associated with index hopping, ensuring reliable multiplexing and enabling the analysis of up to 120 samples in a single run.
Streamlined Workflow for Fast Results
The preparation process for the miRVEL Discovery Small RNA-Seq Library Prep Kit is impressively efficient. Researchers can complete the entire library preparation workflow in less than 7 hours. This speed is achieved by using modified oligonucleotides that prevent the formation of adapter dimers, eliminating the need for labor-intensive gel-size selection. This streamlined protocol allows researchers to quickly and easily ready their samples for sequencing, drastically improving laboratory productivity.
Optimal Performance with Minimal Input
The miRVEL Discovery kit has demonstrated remarkable performance characteristics, showing high correlation data across varying concentrations and outstanding reproducibility among replicates—especially crucial for experiments utilizing very low input biofluids. This newly launched kit not only surpasses competitor offerings but also boasts an exceptional rate of reads mapping to microRNAs (miRNAs). Moreover, it enables a greater number of detected miRNAs in both plasma and blood samples, marking a significant advancement in the capability of RNA sequencing in biomarker discovery.
Availability and Further Information
The miRVEL Discovery Small RNA-Seq Library Prep Kit is now available for purchase. Interested parties can find more detailed information on this cutting-edge product on the official Lexogen website.
About Lexogen
Lexogen stands at the forefront of RNA sequencing technology, dedicated to providing a broad range of innovative solutions for transcriptome analysis and RNA research. Our comprehensive suite of products and services is designed to adapt to the evolving requirements of the scientific community, delivering consistent and reliable results.
For more up-to-date information and news from Lexogen, please visit Lexogen's official website and follow us on social media at @lexogen.
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