#Canada #Toronto #Xtalks #Cell Line Development #Monoclonality Assurance

Enhancing Monoclonality Assurance in Cell Line Development

In an era where biotechnology continues to advance, ensuring the monoclonality of cell lines is critical for the development of therapeutic agents. This upcoming free webinar, hosted by Xtalks, titled "Enhancing Monoclonality Assurance in Cell Line Development: Seeing More at Day-0," aims to provide participants with insights into innovative practices for improving monoclonality assurance. Scheduled for February 24, 2026, the event features prominent speaker Adam Causer, Global Product Manager for the Solentim Portfolio at Nova Biomedical, who will delve deep into the subject.

Monoclonality assurance is vital in confirming that a stable cell line arises from a single progenitor. This assurance is crucial for the manufacture of proteins, cellular therapies, and gene therapies. Issues often arise due to difficulties in confirming true monoclonality, which may lead to project delays and significant increases in risk. The webinar aims to shed light on practical strategies to mitigate false positive results or ghost wells—an issue faced frequently in this domain.

The session will highlight current advancements in imaging technologies, specifically focusing on the use of high-throughput whole well brightfield imaging and nanodroplet techniques. These innovations can dramatically enhance accuracy and reliability in identifying true monoclonality, which is often hampered by conventional methods. Utilizing AI-driven data analytics will also be discussed as a way to streamline the image analysis processes, potentially reducing the need for additional full-time employees by up to 50%.

"Our end-to-end workflow assures a 99.99% probability of clonality," explains Causer. "We digitalize the process of generating evidence for IND submissions, not only making it faster but also more reliable."

Participants will gain actionable insights into minimizing risks associated with ghost wells through automatic, gentle single-cell deposition technologies. The session will also cover how integrating these sophisticated workflows—rooted in comprehensive imaging strategies—can maintain high throughput while enhancing efficiency.

The webinar will be available in two live broadcasts, catering to different time zones. The first session is set for 9 AM CET (4 PM CST in China), and the second session will commence at 8 AM EST (2 PM CET).

In a field where innovation is crucial, Xtalks strives to empower professionals across healthcare sectors with knowledge that facilitates informed decision-making. By promoting collaborative insights, they aim to help move the industry forward. The seminar promises to be an invaluable opportunity for professionals in pharma, biotech, and related fields to stay ahead.

To register for the webinar and learn more about enhancing monoclonality assurance, visit the Xtalks website. Joining this community offers a gateway to the latest in research, trends, and technologies shaping the life sciences landscape today. Don't miss out on the chance to gain essential knowledge from leading experts.

For further details or inquiries about hosting a webinar with Xtalks, interested parties can reach out via the provided contact information. This is your opportunity to enhance your understanding of monoclonality assurance in cell line development through expert guidance and community insights.