Innovative Bonding Peptide and Pinoplex Combination Restores Damaged Hair Strength

Restoring Damaged Hair: The Breakthrough of Ampuleur and Plus Medi

In the world of hair care, the struggle against damaged and weakened hair is a common concern, particularly for those who frequently color their hair or are exposed to harsh environmental factors. Recognizing this issue, Ampuleur, a clinical solution cosmetic brand by 株式会社ハイサイド, has partnered with Plus Medi, a company specializing in open innovation-based dermatological research, to address these hair concerns innovatively. They have opened the Skin Innovation Lab, serving as a hub for cutting-edge research aimed at developing advanced skincare and hair care solutions.

Recent collaborative efforts between the two companies led to a significant breakthrough: the identification of a complex consisting of Bonding Peptide (Tetrapeptide-97 or TP-97) and Pinoplex. This innovative composite demonstrates the ability to repair the internal bonds of damaged hair keratin, thereby revitalizing its strength and structure.

Understanding TP-97 and Pinoplex Combines

What is TP-97?

TP-97 is a pioneering peptide that penetrates deep into damaged hair to mend disulfide bonds (S-S connections) at a molecular level, essential for maintaining the strength and integrity of keratin, the main component of hair.

Introduction of Pinoplex

Pinoplex, derived from the biomimetic extract of pine cones, showcases remarkable properties, including its ability to open and close based on moisture levels. This characteristic makes it an effective ingredient for retaining hair moisture and reattaching cuticles, which are vital for preventing split ends and frizz.

Research Background

Hair predominantly consists of protein, accounting for roughly 85% of its composition. External factors—such as hair dye, sun exposure, and heat styling—can weaken these structural connections, leading to frizz and breakage. Given this context, Ampuleur adopted a skin science perspective to improve hair care solutions, leveraging their expertise in skincare.

The focus on the novel TP-97 peptide emerged from developments in scalp care. Combining this with the moisture-binding properties of Pinoplex, the researchers embarked on a quest to create a synergistic composite aimed at repairing damaged keratin bonds.

Key Findings

1. Repair of Damaged Keratin

Utilizing Fourier Transform Infrared Spectroscopy (FTIR), researchers quantitatively analyzed the impact of the TP-97 and Pinoplex composite on damaged hair samples. When TP-97 and the composite were introduced to bleached human hair keratin extracts, there was a significant reduction in reduced keratin (SH) and an increase in healthy keratin (S-S), evidencing effective repair of damaged keratin bonds.

2. Specific Binding to Damaged Cuticles

Further exploration revealed that the red-fluorescent labeled TP-97 exhibited a strong affinity for the keratin of damaged cuticles, confirming its targeted action in areas most in need of repair.

3. Visualization of Cortex Damage Repair

An innovative staining technique allowed researchers to visualize the repair of the cortical damage within hair. When comparing untreated virgin hair to bleached samples, the latter exhibited notable fluorescence. However, treatment with the TP-97 composite resulted in a reduced fluorescence intensity, indicating effective repair of damaged zones.

Future Directions and Commitment by Ampuleur

With the recent findings, Ampuleur aims to incorporate these groundbreaking insights into the development of advanced hair care products. By collaborating closely with Plus Medi, they plan to enhance existing formulations and develop new products that ensure scientific credibility and effectiveness.

The commitment is to extract the potential of known beneficial ingredients and pursue continuous research and innovation to address diverse consumer needs, reflecting the ever-changing landscape of beauty and wellness.

About Ampuleur

Ampuleur represents a fusion of knowledge from various experts in dermatology and cosmetic science. With a strong belief in the emerging definitions and diversities of beauty, their mission is to provide high-quality products that blend clinical functionality with exceptional sensorial experiences. For more information, visit their official site: Ampuleur Official Site.

Company Overview

株式会社ハイサイド, established in 2003, has been at the forefront of developing cutting-edge, high-performance cosmetics, including its flagship line, AMPLEUR. Their formulas are backed by extensive research and development, catering to a wide spectrum of beauty, health, and medical services. For more details, check here.