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Revolutionary Micro LC Columns for Enhanced Biomarker Analysis

Phenomenex Inc., a key player in advanced analytical technologies, has unveiled its latest innovation: the 0.15 mm ID Micro LC Columns and Micro Traps, tailored for low-flow applications. This introduction marks a significant enhancement for scientists involved in proteomics, metabolomics, and oligonucleotide analysis, promising advanced performance that tackles the everyday challenges faced in these fields.

The new micro columns, based on a core-shell design, optimize the flow rate between 1 to 5 µL/min, showcasing remarkable efficiency compared to the widely-used traditional microflow columns. The columns come in various options, including Kinetex 2.6 µm XB-C18, EVO C18, and F5 variants, with plans to release Luna Omega 1.7 µm PS-C18 soon, providing extensive choice for researchers across diverse reversed-phase applications.

Dr. Tasso Milliotis, a Principal Scientist at AstraZeneca, highlighted the capabilities of the Kinetex 150 x 0.15 mm capillary LC column, emphasizing its robustness and its high separation performance that excels under demanding conditions typical in biomarker analysis. He pointed out the column's ease of integration into low-flow LC-MS systems, noting that its female connectors allow for seamless compatibility, thus simplifying the process of switching between systems.

To further expand its offerings, Phenomenex has introduced innovative micro and nano traps designed with integrated fittings compatible with a wide range of instruments. These traps boast an impressive phase selectivity range, adeptly bridging the gap between nano and micro-flow applications. This means users can expect the highest performance when conducting low-dispersion separations.

These new columns and traps can withstand pressure levels reaching 15,000 psi, ensuring durability and reliability in consistent use. Coupled with low solvent consumption, these products promise enhanced sensitivity, ultimately facilitating more precise analytical outcomes. The need for low-flow chromatography is increasingly acknowledged in various research fields, where accurate biomarker tracking is essential.

The launch of these innovative products at ASMS reflects Phenomenex's commitment to supporting researchers in their quest for breakthroughs. Whether in pharmaceutical development or environmental analysis, the micro LC columns and traps provide solutions tailored for high-sensitivity applications that enhance analytical workflows. By developing chromatography solutions that push the boundaries of current scientific capabilities, Phenomenex continues to lead the field of separation sciences.

In conclusion, Phenomenex's 0.15 mm ID Micro LC Columns and Micro Traps are poised to transform how scientists conduct low-flow analytics. With their notable advances in performance and compatibility, these products are set to be essential tools in laboratories aiming for accuracy and reliability in their biomarker analysis tasks.