#USA #Engineering #Bethlehem #Bioprocess #ABEC

ABEC Expands Its Process Sciences Group

ABEC, a leading name in biotechnological process solutions, announced significant expansions to its Process Sciences Group. This enhancement is directed at strengthening capabilities in bioprocess optimization, crucial for supporting biopharmaceutical manufacturers in their development journeys.

The Process Sciences team uniquely blends chemistry and bioengineering expertise with advanced modeling, experimental testing, and customized equipment design. This combination empowers clients at every stage, from early development to commercial production. Leveraging practical testing alongside computer-driven tools allows ABEC to expedite troubleshooting, ensure efficient scaling, and facilitate reliable technology transfer while maintaining consistent product quality.

Central to ABEC's approach in Process Sciences is a profound understanding of bioprocesses. Engineers meticulously analyze and fine-tune essential parameters such as mass transfer, agitation, mixing time, shear stress, and CO₂ stripping. This attention to detail helps achieve specific process objectives and circumvent common challenges encountered during mixing and scaling.

The team's insight spans microbial fermentation and animal cell culture processes. This breadth allows ABEC to provide tailored solutions suitable for a diverse array of bioproduction applications. Their specialized equipment underscores process validation through hands-on mixing experiments, as well as trials involving living cells or microorganisms, accommodating scale ranges from 200 ml to 6,000 liters.

Complementing these hands-on efforts are numerical flow simulations (Computational Fluid Dynamics, or CFD) and other modeling tools that yield valuable data supporting Quality by Design initiatives and process characterization. Advanced CFD simulations help reduce development time and associated costs by minimizing the number of trials needed, thereby lowering the risks linked to scaling and technology transfer decisions.

Instead of molding processes to fit standard equipment designs, ABEC creates systems tailored to specific process needs. As Scott Pickering, an ABEC spokesperson, stated, "Process Sciences gives our clients confidence in the transition from development to production. By merging modeling, experimental validation, and custom equipment manufacturing, we optimize performance, increase yields, and mitigate uncertainties."

About ABEC

Founded in 1974, ABEC has been at the forefront of providing custom process solutions and services for the global biotech sector. Many top pharmaceutical and biotech companies around the world are ABEC clients, with numerous leading therapies being produced using systems and procedures developed with ABEC technology. The company’s value proposition is built on extensive experience, deep in-house expertise, and a flexible, tailored approach that minimizes costs and market entry times while maximizing productivity.

For further information, you can refer to ABEC's official platforms.