#USA #Cincinnati #Molecular Diagnostics #Meridian Bioscience #Enzyme Stabilization

Meridian Bioscience's New Services

Meridian Bioscience, Inc., a recognized name in the diagnostics industry, has recently expanded its capabilities by introducing advanced enzyme stabilization services. This initiative is aimed at assisting assay developers who are working with crucial technologies such as quantitative Polymerase Chain Reaction (qPCR), isothermal amplification, and next-generation sequencing (NGS). The new services are designed to enhance assay stability, lower limits of detection (LOD), and optimize cost-efficiency, empowering developers to significantly improve their workflows.

Expanding Enzymatic Solutions

With decades of expertise in enzyme development, Meridian is well-equipped to provide comprehensive reagent customization. This means that assay developers can now transition seamlessly from traditional wet chemistry methods to more advanced ambient temperature-stable formats without losing performance standards.

Meridian's innovative stabilization solutions, specifically technologies like lyophilization and air-drying, cater to various applications in both infectious disease diagnostics and oncology. These techniques not only improve enzyme stability but also extend shelf life and eliminate the need for cold-chain logistics. Moreover, reducing manufacturing complexity and associated costs are additional benefits realized through this transition.

By offering ambient temperature-stable formats, Meridian simplifies assay workflows. Developers can forgo the tedious processes of thawing and aliquoting reagents, thereby streamlining operations and speeding up implementation timelines.

Benefits of Ambient Temperature-Stable Assays

The significance of ambient temperature-stable assays in today’s diagnostics landscape cannot be overstated. For developers optimizing existing assays or creating new formats, Meridian offers tailored solutions that align with the evolving demands within the diagnostics sector.

Utilizing proprietary glycerol-free enzyme technology, coupled with specialized buffer formulations, Meridian enables unmatched flexibility and reliability. Key advantages of these types of assays include:

• - Enhanced Stability & Shelf Life: Meridian’s expert methodologies ensure that the reagents maintain their efficacy and consistency even when faced with challenging storage and transport conditions. This advancement allows for simple global distribution without the need for cold storage.
• - Performance Preservation: The techniques used by Meridian during the enzyme stabilization process ensure that the integrity and sensitivity of the assay are not compromised. This is especially pertinent in applications involving infectious diseases and oncology where the detection of low-abundance targets is critical.
• - Cost Savings and Operational Efficiency: Switching to ambient-temperature-stable reagents allows developers to significantly cut cold-chain logistics costs, streamline inventory management, and optimize manufacturing processes all while hastening the market entry of diagnostic assays.

Comprehensive Support Structure

Meridian offers an extensive service model geared toward supporting assay developers at every stage of their transition. This support includes direct access to enzyme expertise, collaboration opportunities to optimize assay protocols, and tailored reagent formulation processes. Furthermore, Meridian's vertically integrated supply chain ensures that developers have reliable access to high-quality enzymes and buffers, thereby reducing their dependency on multiple suppliers.

Revolutionizing the Diagnostics Landscape

Dr. Lourdes Weltzien, President of the Life Science Division at Meridian Bioscience, emphasizes the increasing demand for reliable and stable molecular assays. She notes, "With our advanced enzyme stabilization technologies, we empower developers to enhance the stability, sensitivity, and cost-effectiveness of their assays without compromising performance. Our customized services facilitate a seamless shift from wet chemistry to more stable formats, opening up new avenues for molecular diagnostics."

These innovative services are ideally suited for various stakeholders in the diagnostics field, including diagnostic assay manufacturers, Contract Development and Manufacturing Organizations (CDMOs), Contract Research Organizations (CROs), and pharmaceutical companies that are developing companion diagnostics.

To further explore Meridian’s stabilization services, you can visit www.meridianbioscience.com/stabilizationservices.

About Meridian Bioscience, Inc.

Headquartered in Cincinnati, Ohio, Meridian Bioscience is a fully integrated life science company that develops and markets a diverse array of diagnostic and life science products. Their work spans human, animal, plant, and environmental applications, supporting various diagnostic manufacturers, biotech firms, and research institutions around the globe. Through their commitment to discovery and development, Meridian provides essential raw materials used in numerous immunological and molecular tests, reaching customers in over 70 countries worldwide.