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Online Seminar on Scaling Up Cell Culture Techniques

The I.R. Engineering Education Institute is hosting an engaging online seminar aimed at providing essential knowledge and techniques for scaling up cell culture processes. This seminar is especially relevant for professionals involved in the production of antibody drugs and regenerative medicine cells, where scaling laboratory conditions to actual production scales is increasingly crucial.

As cell culturing scales up, various challenges emerge that are often not apparent at laboratory scales, including issues related to oxygen supply, stirring, temperature regulation, pH control, and cellular loads. To achieve stable production, it is essential to move beyond reliance on experience and to design equipment, operations, and culture conditions based on material balances and kinetics.

Seminar Overview

• - Seminar Title: Troubleshooting and Condition Setting for Scaling Up from Lab to Production in Cell Culture
• - Format: Online (Live Zoom Broadcast and Archive)[
• - Live Date: October 29, 2026, from 1:00 PM to 5:00 PM
• - Archive Availability: November 2 to November 16, 2026
• - Fee: ¥49,500 (tax included)
• - Instructor: Eiji Nagamori, Professor in the Department of Life Engineering, Osaka Institute of Technology

Detailed Course Content

This seminar will cover foundational aspects of bioreactors, discussing various applications, configurations and selections, operating processes, differences from flask cultures, key operational variables, and controls. Furthermore, it will delve into the concept of specific growth rates and methods for determining them, operational strategies, oxygen supply indicators, and optimization techniques. Key takeaways will include the indicators and considerations associated with scaling up processes, along with practical insights on large-scale cell culture and the application of single-use reactors.

Seminar Program:

1. What is a Bioreactor? (Overview)
1.1. Applications of Bioreactors
1.2. Common Bioreactor Configurations and Selection Methods
1.3. Basic Operational Processes and Tips
1.4. Differences between Flask Cultures and Bioreactors
1.5. Important Operational Variables and Control Implementations

2. Formulating Reactions in Bioreactors and Utilizing Them in Operation Design
2.1. Concept and Determination of Specific Growth Rates
2.2. Types and Selection of Operational Procedures
2.3. Indicators for Oxygen Supply Rates and Methodology
2.4. Case Studies on Optimization Using Specific Growth Rates

3. Methodologies for Scaling Up
3.1. Indicators, Realities, and Considerations for Scaling Up

4. Points to Consider in Large-Scale Culture for Various Cells
4.1. Practicalities and Considerations in Microbial Culture
4.2. Practicalities and Considerations in Animal Cell Culture
4.3. Practicalities and Considerations in iPS Cell Culture
4.4. Single-Use Reactor Insights
4.5. Practicalities and Considerations in Plant Cell Culture

Target Audience

• - Beginners who will need to use bioreactors in their future work
• - Technicians who are already utilizing bioreactors and want to deepen their theoretical understanding
• - Business planners looking to explore the current status and future outlook of bioreactors

For more details about the seminar, please visit this link.

The I.R. Engineering Education Institute continually provides the knowledge and expertise necessary for effective problem-solving in manufacturing through educational services, including seminars and online learning.

Japan I.R. Co., Ltd.
With over 50 years of experience, we offer specialized services centered around patent and intellectual property solutions, technical information analysis, manufacturing education, and the production of technical content, guiding businesses toward proficiency in technical domains.

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• - I.R. Engineering Education Institute
• - Address: 3rd Floor CYK Kanda Iwamotocho, 15-1 Kanda Iwamotocho, Chiyoda, Tokyo 101-0033
• - Phone: 03-6206-4966