Novartis Showcases Innovative Immunology Data at Upcoming AAAAI and AAD Meetings

Novartis Showcases Innovative Immunology Data at Upcoming AAAAI and AAD Meetings



Novartis Pharmaceuticals is set to make significant contributions to the field of immunology by presenting groundbreaking research at two major upcoming conferences: the 2025 American Academy of Allergy Asthma and Immunology (AAAAI) and the 2025 American Academy of Dermatology (AAD) Annual Meeting. The company has announced that it will share findings from 17 abstracts, which include investigator-initiated trials and data from pivotal studies on treatment options for hidradenitis suppurativa (HS) and chronic spontaneous urticaria (CSU).

Highlighting Key Findings


Among the notable presentations scheduled, two-year efficacy and safety results from the Phase III SUNSHINE and SUNRISE trials on the continuous use of Cosentyx® (secukinumab) for HS will be featured. This data aims to provide new insights into how ongoing treatment can enhance patient outcomes.

In conjunction with these results, new analyses of the 52-week data from the REMIX pivotal trials will unveil the clinical impacts of remibrutinib, a novel investigational drug that targets CSU. These insights will focus on its effectiveness in managing the condition and improving patient quality of life.

Aiming for Regulatory Approval


With an eye on the future, Novartis plans to submit regulatory paperwork for remibrutinib as a treatment for CSU in the first half of 2025. This step underscores the company’s commitment to addressing unmet medical needs in immune-mediated diseases.

Angelika Jahreis, Global Head of Development for Immunology at Novartis, emphasized, "Conditions like CSU and HS significantly affect patients beyond just visible symptoms, influencing daily activities and overall well-being." The data shared at these congresses will reflect Novartis's commitment to reimagining medicine for individuals facing immune-related health challenges.

Detailed Abstracts to Watch


At AAAAI, critical abstracts include:
  • - Impact of Remibrutinib on Urticaria Control in Patients with CSU (Abstract #598) - an oral presentation discussing long-term results.
  • - Safety Analysis of Remibrutinib - evaluating its impact on blood cell counts across pooled REMIX trial data (Abstract #592).

For the AAD, other highlighted findings encompass:
  • - Effect of Remibrutinib on Sleep and Daily Activities in CSU patients (Abstract #622) and its early impact on itching and hives (Abstract #P622).
  • - Updated analyses on Cosentyx for HS, showing treatment effects through extended phases (Abstracts #63334, #62149, #63451).

Looking Forward


These findings not only aim to enhance clinical understanding of HS and CSU but also pave the way for improved treatment paradigms. The research contributing to these presentations reflects a comprehensive effort to innovate within the field of immunology, thereby reinforcing Novartis's position as a front-runner in drug development for severe chronic conditions. Overall, these developments exemplify the potential impact of advanced treatments on patients' lives, aligning with Novartis's mission of reimagining medicine.

For those in the medical community, the data unveiled at these conferences will offer fresh perspectives on treatment strategies, shedding light on how new therapies can significantly improve the quality of life for patients suffering from these challenging conditions. Visitors to the congresses can expect in-depth discussions and analyses that will shape future research and therapeutic approaches.

Again, Novartis is demonstrating its leadership and commitment to advancing treatment options for patients with serious immune-mediated diseases, promising a brighter future for those affected by HS and CSU.

Topics Health)

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