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NCCN Champions Enhanced Cancer Treatment Access in Africa

Introduction
In a significant stride towards improving healthcare for patients with cancer, the National Comprehensive Cancer Network® (NCCN®) has made headlines during the 2025 African Organization for Research and Training in Cancer (AORTIC) meeting. Hosted in Hammamet, Tunisia, this gathering spotlighted the collaborative efforts made over recent years to expand access to essential cancer treatments in Sub-Saharan Africa.

Major Developments in Cancer Care
During the event, the NCCN revealed its new International Adaptations of NCCN Guidelines tailored specifically for Sub-Saharan Africa. This adaptation follows a comprehensive modification of the existing NCCN Harmonized Guidelines™. The development has been a joint effort with the African Cancer Coalition and the American Cancer Society, reflecting a growing recognition of the need for localized treatment guidelines that resonate with the region's unique healthcare landscape.
The changes not only signify an evolution of the guidelines but also represent tangible progress made in cancer care, underpinning the commitment of local health ministries, care providers, and global partners. From 2017 to 2024, the percentage of cancer treatment options previously deemed inaccessible has dramatically dropped from 82% to 54%. This remarkable improvement underlines the efforts to establish a more equitable treatment paradigm that can support cancer patients in regions that have previously been underserved.

Key Findings from the AORTIC Conference
Data shared during the AORTIC conference cited advancements in numerous areas critical to cancer treatment, including imaging techniques, biomarker testing, radiation therapy, and systemic treatments. Katy Winckworth-Prejsnar, MPH, Global Program Director for NCCN, remarked, "Many therapies and technologies that were once out of reach are now becoming standard options—thanks to the ongoing dedication of local clinicians, governments, and global partners committed to improving cancer outcomes across Sub-Saharan Africa."
The NCCN guidelines have successfully transitioned from offering baseline recommendations to providing regionally tailored resources that reflect the complexities of cancer care in low- and middle-resource settings. The vibrant exchange at the conference highlighted the collaborative spirit driving this initiative, as well as the need for ongoing work to ensure further access to vital treatments and therapies.

Future Outlook and Continuing Efforts
While the progress made so far is commendable, Winckworth-Prejsnar emphasized the critical need for continued efforts and collaboration among all stakeholders. The NCCN Adaptations for Sub-Saharan Africa serve not only as guidelines but also as a foundation for future advancements in cancer treatment accessibility, aiming to close existing gaps in care.
To access these guidelines and further information, cancer care providers, patients, and caregivers can visit NCCN.org/adaptations or explore additional resources via the NCCN Virtual Library of Guidelines® App. The ongoing commitment of the NCCN to equitably elevate cancer care across the globe stands as a beacon of hope for countless individuals affected by cancer.

Conclusion
The NCCN's initiatives come at a critical juncture when improvements in cancer care access can save lives and transform communities. As Sub-Saharan Africa continues its journey towards comprehensive cancer treatment options, collaborative frameworks and the support of international organizations will be instrumental in achieving a healthier future for all.

By continuing to adapt and respond to the evolving healthcare landscape, the NCCN is not only setting a standard in oncology but is also fostering hope and empowerment for cancer patients in Africa and beyond.