#Japan #Tokyo #Eisai #Pariet #Proton Pump Inhibitor

Eisai Launches Pariet® S: A New Era in OTC Medication

Eisai Co., Ltd., headquartered in Tokyo, has marked a significant milestone by launching 'Pariet® S,' the first proton pump inhibitor (PPI) to be approved for over-the-counter (OTC) sales in Japan. Available in pharmacies and drugstores nationwide, this new medication promises to effectively relieve heartburn and stomach pain caused by acid reflux.

A Breakthrough in OTC Medications
'Pariet® S' is poised to change the landscape of OTC medicines in Japan. It obtained manufacturing and marketing approval on March 21, 2025, becoming the first PPI approved for self-medication in the country. The active ingredient, rabeprazole sodium, works directly on the proton pumps in the stomach that produce acid, addressing the root cause of acid-related discomfort. The formulation is developed with the same potency as prescription medications, ensuring consumers receive effective relief.

How It Works
The specially designed tablets are small and easy to swallow, with just one pill needed per day to provide lasting relief for 24 hours. This convenience is highly appealing for those who struggle with recurrent heartburn or excess stomach acid secretion.

Research and Development
Rabeprazole sodium was developed at Eisai's Tsukuba Research Institute and has been available as a prescription option called 'Pariet' since 1997. It has gained approval in over 100 countries worldwide, providing relief for patients suffering from acid-related disorders. With the introduction of 'Pariet® S,' Eisai is excited to extend its support to everyday consumers seeking relief from gastrointestinal issues.

Addressing Modern Health Challenges
In recent years, dietary habits, stress levels, and decreasing rates of Helicobacter pylori infections have contributed to an increase in stomach acid production. Additionally, aging has impacted the strength of the lower esophageal sphincter, leading to more people experiencing acid reflux. Given these contemporary challenges, 'Pariet® S' serves as a necessary option in the OTC market, aiming to improve the quality of life for many sufferers of heartburn and gastric discomfort.

Product Overview

• - Name: 'Pariet® S' (OTC switch, pharmacist-guided medication)
• - Active Ingredient: Rabeprazole sodium 10 mg per tablet
• - Additives: Magnesium oxide, Talc, Hydroxypropyl cellulose, D-mannitol, Ethyl cellulose, Carnauba wax, Calcium carmellose, Glycerin fatty acid ester, Titanium dioxide, Iron (III) oxide, Magnesium stearate, Hydroxypropyl methylcellulose phthalate
• - Indications: Stomach pain, heartburn, indigestion.
• - Dosage: Adults (15 years and older) should take one tablet once daily. Do not use for more than two weeks continuously.
• - Packaging: 6 tablets
• - Suggested retail price: 1,480 yen (excluding tax)
• - Product details: https://www.eisai.jp/products/pariets/pariets

With 'Pariet® S,' Eisai is not only providing a new treatment option but also aiming to support individuals in leading comfortable and worry-free lives. The company takes great pride in bringing this innovative solution to the market, encouraging a healthier lifestyle for all.