#United States #St. Louis #multi-omics #Panome Bio #phosphoproteomics

Panome Bio Launches Innovative Phosphoproteomics Platform

In a significant advancement for research in biological sciences, Panome Bio, a prominent name in the field of multi-omics services, has recently announced the launch of its new global phosphoproteomics platform. This initiative promises to provide in-depth and unbiased analyses of protein levels and phosphorylation events, which play a critical role in regulating various biological processes. As many diseases are often influenced by disrupted signaling pathways, the platform opens new avenues for potential drug targets and deeper understanding of treatment responses.

Phosphorylation: A Key Regulatory Mechanism

Phosphorylation is a crucial mechanism through which protein activity and cellular signaling pathways are regulated. "Altered phosphorylation patterns can be indicative of various diseases," stated Gary Patti, Chief Scientific Officer at Panome Bio. Unlike traditional methods that rely on antibody or aptamer-based approaches to assess proteomes, this new platform utilizes mass spectrometry-based proteomics. This allows for the global measurement of phosphorylation across thousands of proteins, offering a more comprehensive view into human health than ever before.

The significance of this technology cannot be overstated. The capability of analyzing both protein expression levels and post-translational modifications like phosphorylation allows researchers to gain unprecedented insights into molecular mechanisms that underlie health and disease.

Advanced Technology and High Coverage

Panome Bio's phosphoproteomics service stands out due to its high coverage and affordability. By employing advanced liquid chromatography-mass spectrometry (LC/MS) techniques alongside sophisticated computational algorithms, the platform can routinely detect an impressive 15,000 phosphosites and 7,000 unique proteins per sample. This extensive data collection is translated into actionable insights using proprietary analysis methods, including pathway analysis, network mapping, and kinase activity assessments.

Moreover, these phosphoproteomics data contribute significantly to Panome Bio’s multi-omic integration platform, which integrates various types of omics data to uncover novel scientific insights across different research areas.

Key Features of the Global Phosphoproteomics Service

1. Comprehensive Identification: Regular detection of 15,000 phosphosites and 7,000 proteins enhances the array of insights available to researchers.
2. Insightful Data Analysis: The service includes detailed analyses such as differential expression studies, pathway and network mapping, and expert scientific interpretation.
3. Broad Applicability: The platform is compatible with diverse sample types and species, increasing its utility across various research domains.
4. Seamless Integration: It integrates smoothly with other services such as Next-Generation Metabolomics®, Lipidomics®, transcriptomics, and custom datasets.

The Role of Panome Bio in Research

Founded to support researchers in disease and drug development, Panome Bio offers contract research services that encompass metabolomics, proteomics, and integrated multi-omics data analysis. Their comprehensive workflow guides clients from experimental design through sample preparation and data analysis, ensuring that they have access to the most relevant and impactful insights possible.

As the demand for sophisticated analytical tools in life science research continues to grow, Panome Bio is positioning itself at the forefront of innovation. Their new global phosphoproteomics platform not only enhances the accessibility of advanced proteomics but also aims to accelerate discoveries that can ultimately impact patient care and therapeutic strategies. For more information on their services, interested parties can visit Panome Bio's website or reach out via LinkedIn.

Conclusion

In summary, Panome Bio's addition of global phosphoproteomics to its portfolio is a significant leap towards better understanding the molecular underpinnings of diseases. With its ability to provide extensive analyses and integration capabilities, researchers now have a powerful tool to aid in their quest for answers in the complex interplay of protein dynamics in health and disease.