#Switzerland #Basel #Pharmaceutical Innovation #Jungbunzlauer #Tricalcium Citrate

Jungbunzlauer's Tricalcium Citrate Excipient: A Breakthrough in Tablet Manufacturing

In the fast-paced world of pharmaceuticals and nutraceuticals, optimizing tablet manufacturing processes is increasingly essential. Jungbunzlauer, an esteemed leader in sustainable ingredient production, has recently collaborated with Professor Karl Wagner from the University of Bonn to unveil compelling research on their tricalcium citrate excipient, known as TCC TB. This innovative ingredient has shown exceptional results in direct compression studies, setting a new standard for tablet production efficiency and quality.

The results of this collaboration were formally announced on October 29, 2025, at a press conference in Basel, Switzerland. According to Markus Gerhart, the Senior Director at Jungbunzlauer, the research underscores the company’s relentless commitment to scientific rigor, innovation, and excellence in product development. He expressed, "We are proud to demonstrate that our TCC TB delivers reliable performance in direct compression, helping our customers achieve efficiency, quality, and confidence."

Understanding Direct Compression

As known within the industry, direct compression has become the favored method of tablet production indeed due to its myriad benefits, particularly its efficiency and ability to handle sensitive ingredients without compromising quality. However, to achieve optimal results, excipients must possess outstanding flow properties and compactibility. This is where Jungbunzlauer's TCC TB excels.

The rigor of the studies led by Professor Wagner's team revealed that TCC TB exhibits outstanding flowability, impressive tablet strength even under low compression forces, and rapid disintegration rates. These attributes prove particularly crucial for formulators working with challenging compositions like minitablets, moisture-sensitive active pharmaceutical ingredients (APIs), and various botanical actives.

Vegan and Allergen-Free Certification

What further enhances the appeal of tricalcium citrate is its production method. TCC TB is derived from the complete neutralization of citric acid using a high-purity calcium source. This unique process ensures that the product is certified vegan while also being free from allergens and genetically modified organisms (GMOs). Additionally, it complies with the stringent standards outlined by the United States Pharmacopeia (USP), the Food Chemical Codex (FCC), and European standards, making it an attractive option for manufacturers aiming for optimal compliance.

Industry Impact and Future Prospects

The findings from this collaboration will be presented at the CPHI Global event, taking place in Frankfurt from October 28 to 30, 2025, where attendees will have the opportunity to discuss these promising results with Jungbunzlauer representatives. The industry is eager to see how this new data can aid in addressing the challenges faced during tablet formulation and production processes.

Jungbunzlauer’s commitment to research and development is evident as it continually seeks to enhance the quality of ingredients integral to everyday life. With over 150 years of experience in crafting high-quality sustainable ingredients, the company now caters to a wide variety of markets—including food, health, and personal care—demonstrating its versatility and adherence to evolving consumer needs.

In conclusion, Jungbunzlauer's TCC TB stands to fundamentally redefine the tablet production landscape in pharmaceuticals and nutraceuticals. As the industry gravitates toward more efficient and sustainable practices, innovative solutions like TCC TB not only promise enhanced performance but also support manufacturers in meeting compliance and health standards—a vital aspect in today's market landscape. With dedicated leadership and pioneering research collaborations, Jungbunzlauer remains poised at the forefront of the industry’s evolving narrative, paving the way for future advancements in pharmaceutical technology.