New Study Reveals Link Between Epstein-Barr Virus and Lupus Development

Understanding the Connection between Epstein-Barr Virus and Lupus



Introduction


Recent research funded by the Lupus Research Alliance has uncovered significant findings linking the prevalent Epstein-Barr Virus (EBV) with the development of lupus, a chronic autoimmune disorder affecting millions. This study, published in Science Translational Medicine, was spearheaded by Dr. William Robinson at Stanford University.

The Relationship Between EBV and Lupus


The Epstein-Barr Virus is one of the most common viruses globally, infecting over 94% of people. Traditionally understood as a contributor to various diseases, EBV's precise role in triggering autoimmunity, particularly in systemic lupus erythematosus (SLE), remained elusive. This study has filled a critical gap in understanding the mechanisms underlying this relationship.

Dr. Robinson's team discovered that EBV can infect B cells—crucial components of the immune system—and transform them into

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