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Introduction of Spindle

Samyang Roundsquare has made a significant stride in the health and wellness sector with the introduction of Spindle, a revolutionary metabolic health brand aimed at transforming how we perceive strength as we age. Its first product, Spindle Muscle+, is developed to enhance muscle power through a scientifically-backed approach, recognizing the vital gut-muscle connection.

The Gut-Muscle Connection

Traditionally, discussions around muscle health have revolved around increasing physical activity and protein intake. However, recent scientific studies highlight a pivotal factor: the gut-muscle connection. This research demonstrates that what occurs in our gut is fundamental to muscle health, playing a crucial role in protein synthesis, controlling systemic inflammation, and facilitating muscle preservation as we age.
By harnessing this concept, Spindle Muscle+ aims to provide a comprehensive solution for maintaining muscle strength.

Understanding Muscle Decline

Interestingly, muscle strength begins to decline as early as our mid-30s, creating a ripple effect that affects mobility, metabolic health, and overall longevity. While most dietary supplements focus narrowly on nutrients, Spindle boldly addresses the deeper biological systems affecting muscle function. In contrast, Spindle Muscle+ is the first postbiotic supplement specifically designed to support the gut-muscle connection, providing a novel, science-led solution.

Akkermansia MYO™: The Science Behind Spindle Muscle+

Central to Spindle Muscle+ is Akkermansia MYO™, a pasteurized postbiotic derived from the beneficial gut microbe Akkermansia muciniphila. This microbe is known for promoting gut barrier integrity and overall metabolic health. Notably, levels of Akkermansia in the body typically decline with age. As a result, Spindle Muscle+ seeks to restore these levels through rigorous scientific research.

Recent clinical trials, which involved a gold standard methodology over 12 weeks with randomized, double-blind, placebo-controlled conditions, showcased impressive results in adults aged 60 and above. Key findings included:

• - A 10.4% increase in hamstring strength compared to the control group.
• - A 14.1% boost in muscle power.
• - Notable improvements in grip strength by 5.0% points.
• - An increase of 5.6% points in prealbumin levels, an essential biological marker for muscle maintenance and repair.
• - A significant decrease of 37.8% in myostatin levels, a regulator of muscle growth that can impede muscle development when elevated.

Target Audience

Spindle is tailored for health-conscious adults, particularly in their 40s and 50s, who are proactively seeking longevity solutions rather than waiting to counteract decline. This emerging cohort seeks not just fragmented wellness products but scientifically validated options that help maintain their vitality for both work and family commitments. Moreover, Spindle Muscle+ is also suitable for individuals on GLP-1 medications, who face increased risks related to muscle loss when undergoing fluctuations in weight—a significant gap in the current supplement market.

Commitment to Quality

In producing Spindle Muscle+, Samyang Roundsquare adhered to rigorous formulation standards, ensuring that the product is gluten-free and non-GMO. The company has excluded common allergens such as eggs, soy, wheat, nuts, fish, and shellfish, as well as artificial sweeteners, color additives, and preservatives. It is manufactured in a GMP-certified facility, reflecting strict quality control measures, and is developed with oversight from the FDA through its New Dietary Ingredient (NDI) program.

Unlike conventional probiotics, Spindle Muscle+ utilizes a heat-stabilized postbiotic process to guarantee stability and ensure accurate dosing capacity for up to two years. This means consumers can enjoy effective nutritional support conveniently, without concerns of refrigeration.

Backed by Expertise

Spindle emerges from the innovative corridors of Samyang Roundsquare, an internationally recognized food and healthcare powerhouse dedicated to science-driven advancements in nutrition.
As stated by Ahjin Kim, PhD, Head of R&D at Samyang Healthcare, “Muscle health is intertwined with biological systems that we are only just beginning to fully understand, notably the gut-muscle connection. The clinical research surrounding Akkermansia MYO™ provides the essential validation needed to develop a product that consumers can trust. Spindle Muscle+ showcases our promise to formulate based on hard data rather than conjectures.”

For those interested in elevating their strength as they age, Spindle Muscle+ represents an innovative choice rooted deep in scientific research. To learn more or to purchase, visit us.spindle.bio