#United States #Minneapolis #Bio-Techne #Leica Biosystems #ProximityScope

Bio-Techne Launches ProximityScope™ Assay

Bio-Techne Corporation has recently unveiled its innovative ProximityScope™ assay, specifically designed for integration with the BOND RX staining platform offered by Leica Biosystems. This groundbreaking assay marks a significant advancement in spatial protein-protein interaction research, enabling scientists to visualize these interactions with unparalleled clarity at subcellular resolution.

What is ProximityScope™?

The ProximityScope™ assay serves as a transformative tool that provides clear visual signals when two proteins of interest are located close to one another. This unique capability reveals biological interactions that were previously difficult to study using traditional techniques. By working seamlessly with the BOND RX staining system, the ProximityScope™ greatly enhances the detection of proteins and RNA within the same fixed tissue section, offering a powerful multiomic approach.

Integration with Advanced Technologies

By automating the ProximityScope™ assay on the BOND RX platform, Bio-Techne and Leica Biosystems aim to provide researchers with a reliable and high-throughput solution. Karan Arora, Senior Vice President at Leica Biosystems, emphasizes the importance of this partnership, highlighting how it combines Leica's expertise in automation with Bio-Techne's advanced assay technology. This collaboration promises to bring essential scale and consistency to spatial biology research, ultimately accelerating discovery and innovation in the field.

Traditional Methods vs ProximityScope™

Traditional methods for studying protein interactions, such as bulk pull-down assays or non-spatial proximity assays, often lack localization data or require the use of dissociated cells that sacrifice spatial orientation. In contrast, the ProximityScope™ assay addresses these shortcomings by offering high sensitivity, specificity, and low background noise, thus providing researchers with a more accurate picture of protein interactions.

Impact on Research and Therapeutics