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The Journal of Independent Medicine Embarks on Year Two with New Insights and Research

The Independent Medical Alliance (IMA) has unveiled the latest volume of the Journal of Independent Medicine, marking the release of its fifth issue and the commencement of its second year of publication. With the aim of championing conflict-free and rigorous scientific research, this publication is tailored for the use of clinicians and patients who seek objective information in the healthcare sphere. This recent issue, titled Volume 2, Issue 1, aims to address existing uncertainties in medical science and provides a platform for transparent inquiry.

Dr. Joseph Varon, Editor-in-Chief of the Journal and President of IMA, stated, “As we enter our second year, our dedication to Honest Medicine, conflict-free science, and adherence to high standards of rigor continues unabated. We have received outstanding submissions from experts across the globe, representing a wealth of knowledge and insights.” Each issue emphasizes varied submissions that not only enhance understanding but also challenge existing medical assumptions, ultimately striving to improve patient care.

In 2026, the Journal plans to publish four quarterly issues alongside two special editions that shine a light on pressing topics within clinical need. Areas of focus include the management of post-vaccine complications and the use of repurposed drugs and nutraceuticals amidst the chronic disease epidemic.

One of the exciting elements of the new issue is its cover, which illustrates an evolution in both visual and intellectual representation. In contrast to last year's cover, which symbolized the journey toward Honest Medicine, this year's design helps convey what has been cultivated through that journey. Dr. Varon remarked, “The cover symbolizes unity among various clinicians, merging different perspectives that uphold mutual values of truth, transparency, compassion, and respect for patient autonomy.” This design embodies a collaborative effort rather than a singular voice, emphasizing a framework of trust among diverse experts committed to robust scientific research.

Featured Articles of Volume 2, Issue 1 (2026)

Among the significant articles published in this edition are:

• - RNADNA Hybrids Survive Digestion in mRNA Vaccine Manufacturing

- Researchers Kevin McKernan, Charles Rixey, and Jessica Rose reveal findings indicating the presence of residual DNA-related impurities in tested mRNA vaccine lots, calling for revised quantification methods to accurately gauge contamination levels.

• - Detection of SARS-CoV-2 from Patient Fecal Samples by Whole Genome Sequencing

- This study conducted by Andreas Papoutsis and colleagues reports 100% concordance between stool NGS and nasopharyngeal RT-PCR tests, paving the way for potential advancements in fecal genomic detection of SARS-CoV-2.

• - Referendum on Euthanasia and Assisted Suicide Between False Autonomy, Systemic Withdrawal of Treatment, and Economic Pressure

- Andraž Teršek provides an in-depth analysis of Slovenia’s 2025 referendum process, positing that frameworks for assisted death may unintentionally replace comprehensive end-of-life care amidst systemic pressures.

• - Pre-Existing Immunity to COVID-19 Overview and Implications – Part 2

- Dr. Rachel Nicoll surveys evidence suggesting that an individual's past infections and microbiome influence both susceptibility and outcomes related to COVID-19. She calls for further research into the causal mechanisms at play.

• - Diagnostic Neutrality or Sociopolitical Conformity? The Depathologisation of Gender Dysphoria

- Authors Max Thompson and Andrew J. Amos argue that recent changes within psychiatric classifications appear to be influenced more by sociopolitical factors than empirical data, advocating for transparency and independence in methodologies.

• - Creatinine-Guided Furosemide Therapy

- Santiago M. Herrero suggests a revolutionary dosing strategy for diuretics in critically ill patients, aiming for an improved safety and effectiveness paradigm.

• - Establishing an Independent Voice in Medicine

- This reflective piece by Matthew Halma and Dr. Varon chronicles the journal's inaugural year, highlighting its essential role in advancing rigorous, transparent academic work on neglected topics.

• - A Prospective Clinical Trial Evaluating a Polyherbal Combination for the Treatment of Opioid Use Disorder

- This article outlines a trial protocol that investigates the efficacy of a polyherbal supplement alongside standard treatment practices for opioid addiction.

• - The Myth of the 'Correct' Sample Size

- Authors L. Prieto Valiente and colleagues challenge traditional notions surrounding sample size justification in research, thus prompting discussion around feasibility and reporting uncertainties.

• - Impact of Acquired Hypernatremia in the ICU on Mortality

- This retrospective analysis reveals a correlation between hypernatremia acquired in the ICU and increased mortality, framing it as a modifiable risk factor that warrants attention.

All issues of the Journal are accessible at www.JIndepMed.org, offering free resources to aid in the advancement of medical science.

About the Journal of Independent Medicine

The Journal of Independent Medicine, published quarterly by the Independent Medical Alliance™ (IMA), serves as a double-blind peer-reviewed journal dedicated to the pursuit of scientific truth. With no pharmaceutical sponsorship and a strong commitment to ideological neutrality, it prioritizes patient welfare and evidence-based research above profits.

About the Independent Medical Alliance (IMA)

The IMA is a nonprofit organization that unites healthcare professionals dedicated to restoring trust and transparency within the medical community. This coalition emphasizes Honest Medicine through patient-centered approaches while advocating for systemic reforms that prioritize long-term health and wellness.